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Benzo[b]thiophene-2-sulfonamide, N-[3-(aminomethyl)phenyl]-5-chloro-3-methyl-
Benzo[b]thiophene-2-sulfonamide, N-[3-(aminomethyl)phenyl]-5-chloro-3-methyl-
CAS No. 2428737-43-1
Benzo[b]thiophene-2-sulfonamide, N-[3-(aminomethyl)phenyl]-5-chloro-3-methyl-( —— )
Catalog No. M28870 CAS No. 2428737-43-1
Benzo[b]thiophene-2-sulfonamide, N-[3-(aminomethyl)phenyl]-5-chloro-3-methyl- directly inhibits InhA and does not require activation by the catalase peroxidase KatG.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 302 | Get Quote |
|
| 10MG | 447 | Get Quote |
|
| 25MG | 714 | Get Quote |
|
| 50MG | 1017 | Get Quote |
|
| 100MG | 1368 | Get Quote |
|
| 500MG | 2673 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBenzo[b]thiophene-2-sulfonamide, N-[3-(aminomethyl)phenyl]-5-chloro-3-methyl-
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NoteResearch use only, not for human use.
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Brief DescriptionBenzo[b]thiophene-2-sulfonamide, N-[3-(aminomethyl)phenyl]-5-chloro-3-methyl- directly inhibits InhA and does not require activation by the catalase peroxidase KatG.
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DescriptionBenzo[b]thiophene-2-sulfonamide, N-[3-(aminomethyl)phenyl]-5-chloro-3-methyl- directly inhibits InhA and does not require activation by the catalase peroxidase KatG.
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In VitroInhA-IN-2 (Compound 23) (200 μM, 48h) inhibits mycolic acid synthesis (33% growth inhibition) in M. tuberculosis H37Ra.
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetCDK
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RecptorCytochrome P450
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Research Area——
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Indication——
Chemical Information
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CAS Number2428737-43-1
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Formula Weight366.89
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Molecular FormulaC16H15ClN2O2S2
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Purity>98% (HPLC)
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Solubility——
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SMILESCc(c(cc(cc1)Cl)c1s1)c1S(Nc1cc(CN)ccc1)(=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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CCT251545
CCT251545 is a potent, orally bioavailable inhibitor of Wnt signaling with IC50 of 5 nM, also is a potent and selective chemical probe for CDK8 and CDK19 with >100-fold selectivity over 291 other kinases; potently inhibits reporter-based readouts of basal WNT pathway activity in LS174T and SW480 cells in the absence of WNT ligand with IC50 of 23 and 190 nM, respectively.
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Indirubin-3-monoxime
Indirubin-3-monoxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.
